The thought may make your stomach churn, but scientists claim that the gas which makes farts smell of rotten eggs could be used to help tackle conditions like diabetes and Alzheimer’s. The gas behind the putrid stench is known as hydrogen sulphide, and is toxic in large quantities.
But researchers claim that if dosed correctly, the gas can help tackle diabetes, strokes, heart attacks and dementia. Professor Matt Whiteman, of the University of Exeter Medical School, explained that when cells become stressed by disease they produce tiny quantities of hydrogen sulphide. This is because the gas helps sustain mitochondria, the powerhouse of a cell, and in turn keep the cell alive. If this process does not happen, the cells die.
Experts at the University have harnessed the power of this process by designing a new compound (AP39). “[AP39] slowly delivers very small amounts of this gas specifically to the mitochondria. Our results indicate that if stressed cells are treated with AP39, mitochondria are protected and cells stay alive,” Professor Whiteman said.
Attempting to prevent or reverse damage to mitochondria is vital to treating a variety of conditions such as stroke, heart failure, and dementia Mark Wood of Biosciences, at the University of Exeter, said: “Although hydrogen sulphide is well known as a pungent, foul-smelling gas, it is naturally produced in the body and could be a healthcare hero with significant implications for future therapies for a variety of diseases.”
The study linked to the findings suggests that pre-clinical trials of the method are promising. Lab models of cardiovascular disease show that if AP39 is administered, more than 80% of the powerhouse mitochondria cells survive under otherwise highly destructive conditions.
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